Table 5. Significant Drug Interactions for Drugs Used to Treat or.
Nov 6, 2013. Increases Concentrations of Erythromycin and Co-Administered. Alternative statins such as fluvastatin, rosuvastatin, pravastatin are preferred. Pravastatin official prescribing information for healthcare professionals. with concurrent therapy with either erythromycin, cyclosporine, niacin, or fibrates. Aug 5, 2015. In one of the two interaction studies with pravastatin and erythromycin a statistically significant increase in pravastatin AUC 70% and Cmax.
Concurrent macrolide and statin–a common interaction
Sep 5, 2011. statin four-fold, pravastatin by two- fold and simvastatin by 10-fold.6. A study in which 12 subjects were given erythromycin 500mg three times. OATP1B1 variant and atorvastatin and pravastatin-induced rhabdomyolysis found. clarithromycin and erythromycin significantly increase pravastatin plasma.